Hip implants a bit more likely to fail in women

CHICAGO (AP) — Hip replacements are slightly more likely to fail in women than in men, according to one of the largest studies of its kind in U.S. patients. The risk of the implants failing is low, but women were 29 percent more likely than men to need a repeat surgery within the first three years.

The message for women considering hip replacement surgery remains unclear. It's not known which models of hip implants perform best in women, even though women make up the majority of the more than 400,000 Americans who have full or partial hip replacements each year to ease the pain and loss of mobility caused by arthritis or injuries.

"This is the first step in what has to be a much longer-term research strategy to figure out why women have worse experiences," said Diana Zuckerman, president of the nonprofit National Research Center for Women & Families. "Research in this area could save billions of dollars" and prevent patients from experiencing the pain and inconvenience of surgeries to fix hip implants that go wrong.

Researchers looked at more than 35,000 surgeries at 46 hospitals in the Kaiser Permanente health system. The research, published Monday in JAMA Internal Medicine, was funded by the U.S. Food and Drug Administration.

After an average of three years, 2.3 percent of the women and 1.9 percent of the men had undergone revision surgery to fix a problem with the original hip replacement. Problems included instability, infection, broken bones and loosening.

"There is an increased risk of failure in women compared to men," said lead author Maria Inacio, an epidemiologist at Southern California Permanente Medical Group in San Diego. "This is still a very small number of failures."

Women tend to have smaller joints and bones than men, and so they tend to need smaller artificial hips. Devices with smaller femoral heads — the ball-shaped part of the ball-and-socket joint in an artificial hip — are more likely to dislocate and require a surgical repair.

That explained some, but not all, of the difference between women and men in the study. It's not clear what else may have contributed to the gap. Co-author Dr. Monti Khatod, an orthopedic surgeon in Los Angeles, speculated that one factor may be a greater loss of bone density in women.

The failure of metal-on-metal hips was almost twice as high for women than in men. The once-popular models were promoted by manufacturers as being more durable than standard plastic or ceramic joints, but several high-profile recalls have led to a decrease in their use in recent years.

"Don't be fooled by hype about a new hip product," said Zuckerman, who wrote an accompanying commentary in the medical journal. "I would not choose the latest, greatest hip implant if I were a woman patient. ... At least if it's been for sale for a few years, there's more evidence for how well it's working."

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Online:

Journal: http://www.jamainternalmed.com

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Yen firmer but near lows, Asian shares capped

TOKYO (Reuters) - The yen remained near recent lows on Tuesday, as attention turned to the appointment of a new Bank of Japan governor.

Regional share markets held to tight ranges as the absence of catalysts and a holiday in the U.S. overnight capped demand.

The yen, which has dropped 20 percent against the dollar since mid-November, fell further at the start of the week after financial leaders from the G20 promised not to devalue their currencies to boost exports and avoided singling out Japan for any direct criticism.

The choice of the next BOJ governor and two deputies has drawn market attention as a gauge to how strongly Prime Minister Shinzo Abe is committed to reflating the economy. The G20's message was that as long as Japan pursues aggressive monetary easing to achieve that goal, a weaker yen as a result of such domestic monetary policy will be tolerated, analysts say.

"But that means that some other economy's monetary conditions have been tightened," said Barclays Capital in a note.

"Japan hasn't even changed its policy stance thus far, and the effect of expectations of a looser setting have led to limited moves in domestic interest rates, but the sell-off of the JPY has been marked and has clearly caused unease in other economies."

Market reaction was muted to the release of the minutes of the BOJ's January 21-22 meeting, when the bank set a 2 percent inflation target and pledged to an open-ended quantitative easing from 2014, but the yen was bought when Finance Minister Taro Aso told reporters Japan has no plans to buy foreign currency bonds as part of monetary easing, a trader said.

The dollar was down 0.2 percent to 93.75 yen, but remained near its highest since May 2010 of 94.465 hit on February 11. The euro also eased 0.3 percent to 125.05 yen, below its peak since April 2010 of 127.71 yen touched on February 6.

The MSCI's broadest index of Asia-Pacific shares outside Japan <.miapj0000pus> was nearly flat.

The Nikkei stock average <.n225> opened down 0.6 percent, after closing up 2.1 percent on Monday to approach its highest level since September 2008 of 11,498.42 tapped on February 6. <.t/>

Australian shares <.axjo> inched down 0.1 percent on the back of weakness in metals prices, with investors focusing on local corporate earnings for direction after a three-month rally that has taken the market to 4-1/2 year highs.

Seoul shares <.ks11> opened little changed, and were expected to struggle to find momentum on worries about the weak yen.

"The market has been taking a breather recently after staging a recovery earlier this month," said Lee Jae-man, an analyst at Tong Yang Securities in Seoul. "The weaker yen has been priced in to some extent, and the pace of its fall is expected to slow down."

Disappointing earnings pushed European shares lower on Monday for a third straight session of losses while U.S. markets were closed for the President's Day holiday.

The euro was steady around $1.3348. The currency eased slightly on Monday after European Central Bank President Mario Draghi said in a speech at the European Parliament that "the exchange rate is not a policy target but is important for growth and price stability" and that its rise is "a risk."

The risk of an inconclusive outcome in Italy's election this weekend added to investor concerns.

Sterling hovered near a seven-month low against the dollar touched on Monday after a key policymaker made comments about the need for further weakness, while recent poor data has spurred worries of another British recession.

U.S. crude fell 0.4 percent to $95.47 a barrel.

(Additional reporting by Hyunjoo Jin and Miyoung Kim in Seoul; Editing by Shri Navaratnam)

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Israeli lawmakers to investigate Australian spy mystery

JERUSALEM (Reuters) - Israeli lawmakers announced plans on Sunday to investigate the 2010 jailhouse death of a reported Australian immigrant recruit to the Mossad spy agency.

The statement by Parliament's Foreign Affairs and Defence Committee followed calls by Prime Minister Benjamin Netanyahu at a cabinet meeting to dim a growing media spotlight on the affair he saw as at risk of jeopardizing national security.

The case kept under wraps for two years then publicized by Australian television last Tuesday involves a 34-year-old immigrant, Ben Zygier, said to be a Mossad operative held on suspicion of security offences, who died of what has been labeled an apparent suicide behind bars.

In a terse communique, the legislative panel's subcommittee on intelligence said it has "decided to conduct an intensive examination of all aspects of the incident involving the prisoner found dead in his (prison) cell in December 2010."

While unlikely to have any immediate political consequences the investigation may lead to a wider inquiry with potentially broader repercussions.

Netanyahu's government has restricted reporting in Israel on the case, now overshadowing his victory in a national election held last month, using court gag orders, military censorship and direct requests to news editors.

Such steps have done little to douse demands for the authorities to come clean about the circumstances of Zygier's imprisonment and how he was able to kill himself in a highly-supervised isolation cell.

Without citing the case specifically, Netanyahu said on Sunday he "absolutely trusts" Israel's security services and what he described as the independent legal monitoring system under which they operated.

"We are an exemplary democracy," Netanyahu said in remarks aired by Israeli broadcasters.

"But we are also more threatened, more challenged, and therefore we have to ensure the proper operation of our security branches," Netanyahu also said.

"Therefore I ask over everyone: Let the security services continue working quietly so that we can continue to live in safety and tranquility in the State of Israel."

The few Israeli officials who have spoken of Zygier's case have not denied that he was linked to Mossad, which in early 2010 was accused by Dubai of using Australian passport-holders to assassinate a Palestinian arms procurer in the Gulf emirate.

BETRAYED MOSSAD MISSIONS?

Media reports have speculated that Israel suspected the Melbourne-born Jew of betraying or threatening to divulge Mossad missions, perhaps to Australia's security services, as they probed passport fraud.

Civil liberties groups and some Israeli lawmakers have demanded to know whether Zygier's rights were violated by his months of incarceration under alias.

In an apparent reversal from previous statements, Australian Foreign Minister Bob Carr said on Thursday his ministry had known about Zygier's jailing as early as February 2010. On Wednesday he said Australian diplomats in Israel only found out about the detention after his death in custody later that year.

Avigdor Feldman, an Israeli lawyer with whom Zygier consulted in Ayalon prison, said last week that that meeting was arranged by a "Mossad liaison" and that his client had denied "grave charges" for which he awaited trial.

Feldman also said that Zygier's family, which has declined all comment on the affair, knew about his detention. The incarceration was approved by several Israeli courts.

Two senior cabinet members, Intelligence Minister Dan Meridor and Strategic Affairs Minister Moshe Yaalon, told Israeli media on Saturday the case was rare but lawful.

"There are extreme situations...to do with our security and even the need to preserve human life, when we need to take an extreme step such as this," Yaalon told Channel Two television.

Meridor said that publishing the prisoner's identity would have risked "serious harm to security." He did not elaborate.

Tzachi Hanegbi, a lawmaker from Netanyahu's conservative Likud party said he had never been informed of Zygier's arrest as chairman of the parliamentary defence panel at the time.

"This requires explanation," Hanegbi said. "Usually, every significant subject, whether it is impressive achievements or embarrassing failures, is laid out before the subcommittee."

Former Mossad director Danny Yatom told Reuters the agency was under no legal obligation to brief oversight lawmakers in such circumstances.

(Writing by Allyn Fisher-Ilan and Dan Williams; Editing by Jason Webb)

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See The Dress Only Jennifer Lopez Could Wear

Stylewatch
Style News Now

02/15/2013 at 06:00 PM ET

Dave Allocca/Startraks; Amanda Edwards/WireImage; Jason LaVeris/FilmMagic

Judging by the red carpet looks seen at the Grammys and the creations sent down the runways at New York Fashion Week, we have a sneaking suspicion we’ll be spotting a lot more navy and a lot more menswear-inspired getups in the coming weeks. But there’s one style you can pretty much write off (and don’t expect to see much of it at the Oscars): Studio 54-esque dresses.

Up: Navy Instead of Black. The LBD and LWD better watch out: There’s another shade gunning for the spotlight. This week everyone from Emmy Rossum and Anne Hathaway to Oprah Winfrey and Miranda Lambert slipped into midnight blue. And we totally understand the appeal of the color. It’s a bit more interesting and unexpected than black, but equally flattering on all shapes and sizes.

Up: Menswear-Inspired Looks. Beyoncé wore a pantsuit to the Grammys and a number of other stars (including Jessica Alba, Julianne Hough and Solange Knowles) quickly followed, well, suit. We doubt that tons of actresses will forgo gowns for dude duds at the Oscars, but our money is on at least one woman in menswear on that red carpet.

Down: Disco Ball Dresses. They had their moment, but that moment seems to have passed. So, take a long look at Jennifer Lopez in her printed sequin Preen dress (sparkly enough to be hung from the ceiling over any dance floor) because as amazing as it is, the creation is probably the last you’ll see of its kind for some time.

For more on which trends to follow check out our thoughts on platforms, polka dots, and furry accents.

Tell us: Which trend do you hope to see more of? Vote in our poll below! 

PHOTOS: SEE OUR FAVORITE DRESSES OF AWARDS SEASON — SO FAR!

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UN warns risk of hepatitis E in S. Sudan grows

GENEVA (AP) — The United Nations says an outbreak of hepatitis E has killed 111 refugees in camps in South Sudan since July, and has become endemic in the region.

U.N. refugee agency spokesman Adrian Edwards says the influx of people to the camps from neighboring Sudan is believed to be one of the factors in the rapid spread of the contagious, life-threatening inflammatory viral disease of the liver.

Edwards said Friday that the camps have been hit by 6,017 cases of hepatitis E, which is spread through contaminated food and water.

He says the largest number of cases and suspected cases is in the Yusuf Batil camp in Upper Nile state, which houses 37,229 refugees fleeing fighting between rebels and the Sudanese government.

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Japan stocks rally, yen resumes fall after G20

TOKYO (Reuters) - Japanese shares rallied and the yen fell on Monday after Tokyo escaped direct criticism from its G20 peers on its aggressive reflationary plans that have weakened the currency.

"With Japan, as yet, using various measures to ease monetary conditions domestically, we do not expect a large international backlash against its efforts and look for the JPY to continue to decline gradually as the easier monetary conditions feed through into FX," Barclays Capital said in a note to clients.

The G20 declined to single out Tokyo but committed to refrain from competitive devaluations and said monetary policy would be directed only at price stability and growth. Japan said this has given it a green light to pursue its policies unchecked.

Taking their cue from the G20, the Nikkei average <.n225> opened up 1.3 percent as the yen resumed its downtrend. <.t/>

The MSCI's broadest index of Asia-Pacific shares outside Japan <.miapj0000pus> was nearly unchanged. The pan-Asian index briefly hit a 18-1/2-month high on Friday and had its best performance since the week of January 6 with a 1.2 percent weekly gain.

On Friday, MSCI's all-country world index <.miwd00000pus>, a measure of global equity activity, traded down 0.26 percent, while European shares closed lower and U.S. stocks ended flat.

Australian shares rose 0.3 percent as miners gained on hopes that top customer China might start buying after the Lunar New Year holidays, while blue chips Commonwealth Bank of Australia and Telstra Corp Ltd dropped after trading ex-dividend.

Markets in China and Taiwan resumed trading after a week-long holiday.

In Seoul, the Kospi <.ks11> opened down 0.1 percent, partly weighed by concerns over continued yen weakness that could erode the competitive edge of Korea's exporters.

"There is not much else to go on today except the currency, so everything depends on where the yen goes," said Toshiyuki Kanayama, senior market analyst at Monex.

The dollar rose 0.3 percent to 93.75 yen inching closer to its highest since May 2010 of 94.465 hit on February 11. The euro added 0.1 percent to 125.26 yen, still below its peak since April 2010 of 127.71 yen touched on February 6.

The market's focus is now on Prime Minister Shinzo Abe's nominee for the next Bank of Japan governor. Abe is expected to announce his choice in coming days.

Sources told Reuters that former top financial bureaucrat Toshiro Muto is leading the field of candidates to become the next central bank governor. It is expected that he would intensify stimulus efforts to reflate the economy.

STOCKS CONSOLIDATE

Data from EPFR Global on Friday underscored that a consolidation was underway in global equities after their recent rally. It showed investors worldwide pulled $3.62 billion from U.S. stock funds in the latest week, the most in ten weeks after taking a neutral stance the prior week. But demand for emerging market equities remained strong, with investors putting $1.81 billion in new cash to stock funds, the fund-tracking firm said.

Demand for commodities will likely be in focus as China returns to the market.

Investors are also expected to focus on fiscal talks in Washington, where policymakers are discussing a package of budget cuts set to kick in on March 1. Analysts say the austerity measures could hurt the U.S. economy.

U.S. crude fell 0.2 percent to $95.64 a barrel.

(Additional reporting by Sophie Knight in Tokyo; Editing by Shri Navaratnam)

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Bomb kills 64 in Pakistan's Quetta

QUETTA, Pakistan (Reuters) - Sixty-four people including school children died on Saturday in a bomb attack carried out by extremists from Pakistan's Sunni Muslim majority, police said.

A spokesman for Lashkar-e-Jhangvi, a Sunni group, claimed responsibility for the bomb in Quetta, which caused casualties in the town's main bazaar, a school and a computer center. Police said most of the victims were Shi'ites.

Burned school bags and books were strewn around.

"The explosion was caused by an improvised explosive device fitted to a motorcycle," said Wazir Khan Nasir, deputy inspector general of police in Quetta.

"This is a continuation of terrorism against Shi'ites."

"I saw many bodies of women and children," said an eyewitness at a hospital. "At least a dozen people were burned to death by the blast."

Most Western intelligence agencies have regarded the Pakistani Taliban and al Qaeda as the gravest threat to nuclear-armed Pakistan, a strategic U.S. ally.

But Pakistani law enforcement officials say Lashkar-e-Jhangvi has become a formidable force.

TENSIONS

Last month the group said it carried out a bombing in Quetta that killed nearly 100 people, one of Pakistan's worst sectarian attacks. Thousands of Shi'ites protested in several cities after that attack.

Pakistani intelligence officials say extremist groups, led by Lashkar-e-Jhangvi, have escalated their bombings and shootings of Shi'ites to trigger violence that would pave the way for a Sunni theocracy in U.S.-allied Pakistan.

More than 400 Shi'ites were killed in Pakistan last year, many by hitmen or bombs, and the perpetrators are almost never caught. Some hardline Shi'ite groups have hit back by killing Sunni clerics.

The growing sectarian violence has hurt the credibility of the government, which has already faced criticism ahead of elections due in May for its inability to tackle corruption and economic stagnation.

The schism between Sunnis and Shi'ites developed after the Prophet Muhammad died in 632 when his followers could not agree on a successor.

Emotions over the issue are highly potent even today, pushing some countries, including Iraq five years ago, to the brink of civil war.

Pakistan is nowhere near that stage but officials worry that Sunni extremist groups have succeeded in dramatically ratcheting up tensions and provoking revenge attacks in their bid to destabilize the country.

(Reporting by Jibran Ahmed; Writing by Michael Georgy; Editing by Stephen Powell)

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Oscar Party Idea: Make Sheila G. Main's Truffles

02/16/2013 at 06:30 PM EST

Andrew Purcell; Inset: Courtesy Sheila G. Main

Oscar night is just around the corner so start prepping your viewing party menu now! Take inspiration from any of the films nominated or replicate what Sheila G. Main, the creator of the Original Brownie Brittle snack, will serve at studio head Harvey Weinstein's Oscar party!

Brownie Truffles

Makes 22 to 24 truffles

• 6 oz. semisweet chocolate, chopped
• 2 oz. unsweetened chocolate, chopped
• 8 tbsp. unsalted butter, cut into quarters
• 3 large eggs
• 1 ¼ cups sugar
• 2 tsp. vanilla
• ½ tsp. salt
• 1 cup flour
• 2 tbsp. unsweetened cocoa powder
• 1–2 tbsp. Grand Marnier
• 1 oz. (2 tbsp.) champagne

1. Preheat oven to 350°. Grease an 8x8-in. baking pan. In a bowl, melt chocolates and butter in microwave on high for 2 minutes. Stir until smooth. Let cool.

2. In a large bowl, whisk together eggs, sugar, vanilla and salt. Stir in the chocolate mixture. In a medium bowl, whisk together flour and cocoa powder. Stir it into the chocolate mixture. Do not over mix. Pour batter into pre-pared pan. Bake for 25 minutes. (Brownies will be slightly underbaked.) Let cool.

3. Cut brownies into pieces and mix in food processor, along with Grand Marnier and champagne until creamy. Chill for at least 1 hour. Use an ice cream scoop to make truffles. Roll into balls, then roll in sanding sugar or a coating of your choice.

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UN warns risk of hepatitis E in S. Sudan grows

GENEVA (AP) — The United Nations says an outbreak of hepatitis E has killed 111 refugees in camps in South Sudan since July, and has become endemic in the region.

U.N. refugee agency spokesman Adrian Edwards says the influx of people to the camps from neighboring Sudan is believed to be one of the factors in the rapid spread of the contagious, life-threatening inflammatory viral disease of the liver.

Edwards said Friday that the camps have been hit by 6,017 cases of hepatitis E, which is spread through contaminated food and water.

He says the largest number of cases and suspected cases is in the Yusuf Batil camp in Upper Nile state, which houses 37,229 refugees fleeing fighting between rebels and the Sudanese government.

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G20 steps back from currency brink, heat off Japan

MOSCOW (Reuters) - The Group of 20 nations declared on Saturday there would be no currency war and deferred plans to set new debt-cutting targets, underlining broad concern about the fragile state of the world economy.

Japan's expansive policies, which have driven down the yen, escaped direct criticism in a statement thrashed out in Moscow by policymakers from the G20, which spans developed and emerging markets and accounts for 90 percent of the world economy.

Analysts said the yen, which has dropped 20 percent as a result of aggressive monetary and fiscal policies to reflate the Japanese economy, may now continue to fall.

"The market will take the G20 statement as an approval for what it has been doing -- selling of the yen," said Neil Mellor, currency strategist at Bank of New York Mellon in London. "No censure of Japan means they will be off to the money printing presses."

After late-night talks, finance ministers and central bankers agreed on wording closer than expected to a joint statement issued last Tuesday by the Group of Seven rich nations backing market-determined exchange rates.

A draft communiqué on Friday had steered clear of the G7's call for economic policy not to be targeted at exchange rates. But the final version included a G20 commitment to refrain from competitive devaluations and stated monetary policy would be directed only at price stability and growth.

"The mood quite clearly early on was that we needed desperately to avoid protectionist measures ... that mood permeated quite quickly," Canadian Finance Minister Jim Flaherty told reporters, adding that the wording of the G20 statement had been hardened up by the ministers.

As a result, it reflected a substantial, but not complete, endorsement of Tuesday's proclamation by the G7 nations - the United States, Japan, Britain, Canada, France, Germany and Italy.

As with the G7 intervention, Tokyo said it gave it a green light to pursue its policies unchecked.

"I have explained that (Prime Minister Shinzo) Abe's administration is doing its utmost to escape from deflation and we have gained a certain understanding," Finance Minister Taro Aso told reporters.

"We're confident that if Japan revives its own economy that would certainly affect the world economy as well. We gained understanding on this point."

Flaherty admitted it would be difficult to gauge if domestic policies were aimed at weakening currencies or not.

NO FISCAL TARGETS

The G20 also made a commitment to a credible medium-term fiscal strategy, but stopped short of setting specific goals as most delegations felt any economic recovery was too fragile.

The communiqué said risks to the world economy had receded but growth remained too weak and unemployment too high.

"A sustained effort is required to continue building a stronger economic and monetary union in the euro area and to resolve uncertainties related to the fiscal situation in the United States and Japan, as well as to boost domestic sources of growth in surplus economies," it said.

A debt-cutting pact struck in Toronto in 2010 will expire this year if leaders fail to agree to extend it at a G20 summit of leaders in St Petersburg in September.

The United States says it is on track to meet its Toronto pledge but argues that the pace of future fiscal consolidation must not snuff out demand. Germany and others are pressing for another round of binding debt targets.

"We had a broad consensus in the G20 that we will stick to the commitment to fulfill the Toronto goals," German Finance Minister Wolfgang Schaeuble said. "We do not have any interest in U.S.-bashing ... In St. Petersburg follow-up-goals will be decided."

The G20 put together a huge financial backstop to halt a market meltdown in 2009 but has failed to reach those heights since. At successive meetings, Germany has pressed the United States and others to do more to tackle their debts. Washington in turn has urged Berlin to do more to increase demand.

Backing in the communiqué for the use of domestic monetary policy to support economic recovery reflected the U.S. Federal Reserve's commitment to monetary stimulus through quantitative easing, or QE, to promote recovery and jobs.

QE entails large-scale bond buying -- $85 billion a month in the Fed's case -- that helps economic growth but has also unleashed destabilising capital flows into emerging markets.

A commitment to minimize such "negative spillovers" was an offsetting point in the text that China, fearful of asset bubbles and lost export competitiveness, highlighted.

"Major developed nations (should) pay attention to their monetary policy spillover," Vice Finance Minister Zhu Guangyao was quoted by state news agency Xinhua as saying in Moscow.

Russia, this year's chair of the G20, admitted the group had failed to reach agreement on medium-term budget deficit levels and expressed concern about ultra-loose policies that it and other emerging economies say could store up trouble for later.

On currencies, the G20 text reiterated its commitment last November, "to move more rapidly toward mores market-determined exchange rate systems and exchange rate flexibility to reflect underlying fundamentals, and avoid persistent exchange rate misalignments".

It said disorderly exchange rate movements and excess volatility in financial flows could harm economic and financial stability.

(Additional reporting by Gernot Heller, Lesley Wroughton, Maya Dyakina, Tetsushi Kajimoto, Jan Strupczewski, Lidia Kelly, Katya Golubkova, Jason Bush, Anirban Nag and Michael Martina. Writing by Douglas Busvine. Editing by Timothy Heritage/Mike Peacock)

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